Corpus ID: 45930118

Segregation analysis reveals a major gene effect in compact and cancellous bone mineral density in 2 populations.

  title={Segregation analysis reveals a major gene effect in compact and cancellous bone mineral density in 2 populations.},
  author={G. Livshits and D. Karasik and O. Pavlovsky and E. Kobyliansky},
  journal={Human biology},
  volume={71 2},
Involvement of genetic factors in determining bone mineral density (BMD) is doubtless. However, the exact nature of the genes governing BMD variation and sources for genetic determination of BMD of different parts of bone (compact and cancellous) have not been completely studied. The results of the complex segregation analyses performed in our previous study (Livshits et al. 1996) on a Turkmenian sample strongly support the hypothesis that a single Mendelian locus has a large effect on BMD. The… Expand
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