Segmentation of Noisy Signals Generated By a Nanopore

Abstract

Nanopore-based single-molecule sequencing techniques exploit ionic current steps produced as biomolecules pass through a pore to reconstruct properties of the sequence. A key task in analyzing complex nanopore data is discovering the boundaries between these steps, which has traditionally been done in research labs by hand. We present an automated method of… (More)

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Cite this paper

@inproceedings{Schreiber2015SegmentationON, title={Segmentation of Noisy Signals Generated By a Nanopore}, author={Jacob Schreiber and Kevin Karplus}, year={2015} }