Segmentation and intensity estimation for microarray images with saturated pixels

@inproceedings{Yang2011SegmentationAI,
  title={Segmentation and intensity estimation for microarray images with saturated pixels},
  author={Yan Yang and Phillip Stafford and YoonJoo Kim},
  booktitle={BMC Bioinformatics},
  year={2011}
}
Microarray image analysis processes scanned digital images of hybridized arrays to produce the input spot-level data for downstream analysis, so it can have a potentially large impact on those and subsequent analysis. Signal saturation is an optical effect that occurs when some pixel values for highly expressed genes or peptides exceed the upper detection… CONTINUE READING