Segmental staining of the murine nephron by monoclonal antibodies directed against the GP-2 subunit of laminin.

Abstract

Monoclonal antibodies to GP-2, the 220,000-dalton subunit of laminin, were used in an immunohistologic study to investigate structural variations in basement membranes. Mouse kidney was used because of the wide range of basement membranes represented. Two rat/mouse monoclonal antibodies, designated LAM-I and LAM-II were compared with rabbit polyclonal anti… (More)

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