Segment-specific terminal sequences of Bunyamwera bunyavirus regulate genome replication.

@article{Barr2003SegmentspecificTS,
  title={Segment-specific terminal sequences of Bunyamwera bunyavirus regulate genome replication.},
  author={John N. Barr and Richard M. Elliott and Ewan F Dunn and Gail Williams Wertz},
  journal={Virology},
  year={2003},
  volume={311 2},
  pages={
          326-38
        }
}
Bunyamwera virus (BUNV) is the prototype of both the Orthobunyavirus genus and the Bunyaviridae family of segmented negative sense RNA viruses. The tripartite BUNV genome consists of small (S), medium (M), and large (L) segments that are transcribed to give a single mRNA and replicated to generate an antigenome that is the template for synthesis of further genomic RNA strands. We modified an existing cDNA-derived RNA synthesis system to allow identification of BUNV RNA replication and… CONTINUE READING

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