Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos.

@article{Bejsovec1993SegmentPG,
  title={Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos.},
  author={Amy Bejsovec and Eric F. Wieschaus},
  journal={Development},
  year={1993},
  volume={119 2},
  pages={501-17}
}
Each segment of a Drosophila larva shows a precisely organized pattern of cuticular structures, indicating diverse cellular identities in the underlying epidermis. Mutations in the segment polarity genes alter the cuticle pattern secreted by the epidermal cells; these mutant patterns provide clues about the role that each gene product plays in the development of wild-type epidermal pattern. We have analyzed embryos that are multiply mutant for five key patterning genes: wingless, patched… CONTINUE READING

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