Segment-based dose optimization using a genetic algorithm.

  title={Segment-based dose optimization using a genetic algorithm.},
  author={Cristian Cotrutz and Lei Xing},
  journal={Physics in medicine and biology},
  volume={48 18},
Intensity modulated radiation therapy (IMRT) inverse planning is conventionally done in two steps. Firstly, the intensity maps of the treatment beams are optimized using a dose optimization algorithm. Each of them is then decomposed into a number of segments using a leaf-sequencing algorithm for delivery. An alternative approach is to pre-assign a fixed number of field apertures and optimize directly the shapes and weights of the apertures. While the latter approach has the advantage of… CONTINUE READING


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