Segment-Based Scores for Pairwise and Multiple Sequence Alignments

  title={Segment-Based Scores for Pairwise and Multiple Sequence Alignments},
  author={Burkhard Morgenstern and William R. Atchley and Klaus Hahn and Andreas W. M. Dress},
  journal={Proceedings. International Conference on Intelligent Systems for Molecular Biology},
In this paper, we discuss a novel scoring scheme for sequence alignments. The score of an alignment is defined as the sum of so-called weights of aligned segment pairs. A simple modification of the weight function used by the original version of the DIALIGN alignment program turns out to have a crucial advantage: it can be applied to both, global and local alignment problems without the need to specify a threshold parameter. 
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Incremental Computaton of Transitive Closure and Greedy Alignment

  • S Abdedda’ m
  • Proc . of 8th Annual Symposium on Combinatorial…
  • 1997

Molecular Evolution, Sinauer Associates, Inc

  • Li, W.-H
  • 1997

A general method

  • U. Thnges, S. W. Perrey, J. Stoye, A. Dress
  • 1996

A general method for fast multiple sequence alignment

  • M. Vingron, P. Argos
  • 1996

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