Seeking passe-partout in the catalytic asymmetric aziridination of imines: evolving toward substrate generality for a single chemzyme.

Abstract

The asymmetric catalytic aziridination reaction (AZ reaction) of imines derived from dianisylmethyl (DAM) amine and tetra-methyldianisylmethyl (MEDAM) amine were examined with boroxinate catalysts prepared from both the VANOL and VAPOL ligands. This included an evaluation of different protocols for the preparation of the catalyst. The AZ reaction of DAM and… (More)
DOI: 10.1021/jo101160c

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