SeekTB, a two-stage multiplex real-time-PCR-based method for differentiation of the Mycobacterium tuberculosis complex.

@article{Reddington2012SeekTBAT,
  title={SeekTB, a two-stage multiplex real-time-PCR-based method for differentiation of the Mycobacterium tuberculosis complex.},
  author={Kate Reddington and Alimuddin M. Zumla and Matthew G. D. Bates and Dick van Soolingen and Stefan Niemann and Thomas Barry and Justin O'Grady},
  journal={Journal of clinical microbiology},
  year={2012},
  volume={50 7},
  pages={2203-6}
}
Tuberculosis (TB) in humans is caused by members of the Mycobacterium tuberculosis complex (MTC). The accurate identification of the MTC member causing human infection is important because the treatment of TB caused by some MTC members requires an alteration of the standard drug regimen, it can inform whether transmission is human to human or zoonotic, and it enables accurate epidemiology studies that help improve TB control. In this study, an internally controlled two-stage multiplex real-time… CONTINUE READING
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