Seeing spots: complex phase behavior in simple membranes.

@article{Veatch2005SeeingSC,
  title={Seeing spots: complex phase behavior in simple membranes.},
  author={Sarah L Veatch and Sebastian Keller},
  journal={Biochimica et biophysica acta},
  year={2005},
  volume={1746 3},
  pages={
          172-85
        }
}
Liquid domains in model lipid bilayers are frequently studied as models of raft domains in cell plasma membranes. Micron-scale liquid domains are easily produced in vesicles composed of ternary mixtures of a high melting temperature lipid, a low melting temperature lipid, and cholesterol. Here, we describe the rich phase behavior observed in binary and ternary systems. We then discuss experimental challenges inherent in mapping phase diagrams of even simple lipid systems. For example… CONTINUE READING
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