Seeing hot carriers break the limit.


Viruses compound dietary pathology Reoviruses commonly infect humans and mice asymptomatically. Bouziat et al. found that immune responses to two gutinfecting reoviruses take different paths in mice (see the Perspective by Verdu and Caminero). Both reoviruses invoked protective immune responses, but for one reovirus, when infection happened in the presence of a dietary antigen (such as gluten or ovalbumin), tolerance to the dietary antigen was lost. This was because this strain prevented the formation of tolerogenic T cells. Instead, it promoted T helper 1 immunity to the dietary antigen through interferon regulatory factor 1 signaling. Celiac disease patients also exhibited elevated levels of antibodies against reovirus. —CA and KLM

DOI: 10.1126/science.356.6333.37-d

Cite this paper

@article{Szuromi2017SeeingHC, title={Seeing hot carriers break the limit.}, author={Phil Szuromi}, journal={Science}, year={2017}, volume={356 6333}, pages={37} }