Seeing Patterns: Models, Visual Evidence and Pictorial Communication in the Work of Barbara McClintock

  title={Seeing Patterns: Models, Visual Evidence and Pictorial Communication in the Work of Barbara McClintock},
  author={Carla Christine Keirns},
  journal={Journal of the History of Biology},
  • C. Keirns
  • Published 1 March 1999
  • Biology
  • Journal of the History of Biology
Barbara McClintock won the Nobel Prize in 1983 for her discovery of mobile genetic elements. Her Nobel work began in 1944, and by 1950 McClintock began presenting her work on “controlling elements.” McClintock performed her studies through the use of controlled breeding experiments with known mutant stocks, and read the action of controlling elements (transposons) in visible patterns of pigment and starch distribution. She taught close colleagues to “read” the patterns in her maize kernels… Expand
Blobel and Sabatini’s “Beautiful Idea”: Visual Representations of the Conception and Refinement of the Signal Hypothesis
  • M. Labonte
  • Philosophy, Medicine
  • Journal of the history of biology
  • 2017
The original 1971 model of proteins destined to be secreted from the cell contain a “signal” to direct their release and can be viewed as an epistemic creation, which was ultimately supported by experimental evidence gathered after the speculative model was published. Expand
How Theories became Knowledge: Morgan's Chromosome Theory of Heredity in America and Britain
  • S. Brush
  • Biology, Medicine
  • Journal of the history of biology
  • 2002
The reasons why thechromosome Theory of Heredity was accepted as part of a series of comparative studies of theory-acceptance in the sciences are examined, including the persuasiveness of confirmed novel predictions. Expand
Fedoroff's translation of McClintock: The uses of chemistry in the reorganization of genetics
The case discussed in this essay presupposes the “reduction” of biology to chemistry that produced molecular biology, and studies in particular the effect of translating problems that arose in genetics into the idiom of molecular biology. Expand
Visuals and Visualisation of Human Body Systems
This paper explores the role of diagrams and text in middle school students’ understanding and visualisation of human body systems. We develop a common framework based on structure and function toExpand
Visual and Spatial Modes in Science Learning
This paper surveys some major trends from research on visual and spatial thinking coming from cognitive science, developmental psychology, science literacy, and science studies. It explores the roleExpand


Picturing Time: The Work of Etienne-Jules Marey (1830-1904)
Etienne-Jules Marey was an inventor whose methods of recording movement revolutionized our way of visualizing time and motion. Best remembered for his chronophotography, Marey constructed aExpand
Picturing Weismannism: A Case Study of Conceptual Evolution
The problem of analyzing conceptual change in science has been substantially refined since its introduction by logical empiricists, particularly Karl Popper, and its radical critique by Kuhn.Expand
遺伝子の分子生物学 = Molecular biology of the gene
The long-awaited Fifth Edition of James D. Watson's classic text, Molecular Biology of the Gene, has been thoroughly revised and is published to coincide with the 50th anniversary of Watson andExpand
The Politics of Macromolecules: Molecular Biologists, Biochemists, and Rhetoric
It is shown that not until a generation later, in the 1 960s, did the scientific establishment begin to register and respond to this ongoing restructuring of the scientific order away from traditional disciplinary regimes, with their monopolies over the academic reproduction of "knowledgepower" systems and resulting social control. Expand
The cell-theory; a restatement, history and critique.
  • J. Baker
  • Biology, Medicine
  • The Quarterly journal of microscopical science
  • 1948
A long time elapsed after the discovery of cells before they came to be generally regarded as morphological units, yet diploid and haploid protoplasts (haplocytes and diplocytes) are the primary components of plants and animals and are still retained as such by most organisms. Expand
Refections on Image and Logic: A Material Culture of Microphysics
  • P. Galison
  • Computer Science, Sociology
  • Perspectives on Science
  • 1999
The author describes how the necessity for teamwork in operating multimillion-dollar machines has created dynamic "trading zones", where instrument makers, theorists and experimentalists meet, share knowledge, and co-ordinate the extraordinarily diverse pieces of the culture of modern microphysics - work, machines, evidence and argument. Expand
The Relation between Light Variegated and Medium Variegated Pericarp in Maize.
The present report is based upon a restudy of variegated pericarp in Tmaize, a mutable character which is well known through the important pioneer work of EMERSON (1914, 1917, 1929), and the results obtained bear directly on the allied problem of the kind of change which occurs whenvariegated is transformed to the stable self colored type. Expand
Prints and Visual Communication
The sophistication of the photographic process has had two dramatic results--freeing the artist from the confines of journalistic reproductions and freeing the scientist from the unavoidableExpand
Boris Ephrussi and the synthesis of genetics and embryology.
Boris Ephrussi was a proponent of an integrative view of the organism that left him at odds with his colleagues in genetics, a prime mover in the institutionalization of genetics in France, and closely involved with institutional developments elsewhere that reconfigured the map of biology. Expand
Creative Couples in the Sciences
Can two scientists work and live together? Marie and Pierre Curie proved that it was indeed possible to have a happy marriage and do brilliant research together. This collection of seventeen originalExpand