Seeing Is Believing The Bicoid Morphogen Gradient Matures

  title={Seeing Is Believing The Bicoid Morphogen Gradient Matures},
  author={Anne Ephrussi and D. St Johnston},
Although Cell has a long history of publishing some of the most significant advances in developmental biology, the back to back papers by Driever and Nüsslein-Volhard on the role of the Bicoid gradient in patterning the Drosophila embryo stand out as the first molecular demonstration of two of the longest standing concepts of the field, namely localized cytoplasmic determinants and morphogen gradients. Here we discuss the impact of this ground-breaking work and review recent results on bicoid… CONTINUE READING

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Publications referenced by this paper.
Showing 1-10 of 95 references

, and Schüpbach , implications for axis specification and intercellular transport

S. Roth, F. S. Neuman-Silberberg, G. Barcelo
View 3 Excerpts
Highly Influenced

Dro - tion of both major body axes in Drosophila by gurkentorpedo signalsophila gurken ( TGFalpha ) mRNA localizes as particles that moveling

N. Polariza-MacDougall, A. Clark, E. MacDougall, I. Davis
Nature Dev . Cell • 2003

Hörstadius, S

S. G. Martin, V. Leclerc, K. Smith-Litière, D. St Johnston
(1935). Über die Determination im Verlaufe der EiThe identification of novel genes required for Drosophila anteroposachse bei Seeigeln. Publ. Staz. Zool. Napoli 14, 251–479. terior axis formation in a germline clone screen using GFP-Staufen. • 2003
View 1 Excerpt

Estab- Development 130, 4201–4215

B. Houchmandzadeh, E. Wieschaus, S. Leibler
lishment of developmental precision and proportions in the early Mlodzik, M., and Gehring, W.J. (1987). Expression of the caudal Drosophila embryo. Nature 415, 798–802. • 2002
View 1 Excerpt

to the vegetal hemisphere in Xenopus eggs codes for a growth Gammatubulin 37 C and gammatubulin ring complex protein 75 are factor related to TGF - beta

S. Luschnig, I. Koch, C. Nusslein-Volhard
Cell • 2002

, and Macdonald , sophila embryonic development

X. Zhou, W. Shillinglaw, W. Henzel

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