See no evil, hear no evil, do no evil: the lessons of immune privilege

  title={See no evil, hear no evil, do no evil: the lessons of immune privilege},
  author={Jerry Y. Niederkorn},
  journal={Nature Immunology},
Immune-mediated inflammation and allograft rejection are greatly reduced in certain organs, a phenomenon called 'immune privilege'. Immune privilege is well developed in three regions of the body: the eye, the brain and the pregnant uterus. Immune-mediated inflammation has devastating consequences in the eye and brain, which have limited capacity for regeneration. Likewise, loss of immune privilege at the maternal-fetal interface culminates in abortion in rodents. However, all three regions… CONTINUE READING

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