Sedative effects of the dopamine D1 receptor agonist A 68930 on rat open‐field behavior

@article{Salmi2000SedativeEO,
  title={Sedative effects of the dopamine D1 receptor agonist A 68930 on rat open‐field behavior},
  author={Peter Salmi and Sven Ahl{\'e}nius},
  journal={NeuroReport},
  year={2000},
  volume={11},
  pages={1269–1272}
}
The present results demonstrate sedative effects of the DA D1 receptor agonist A 68930 (0.9–15 μmol kg-1, s.c.) on rat spontaneous locomotor activity in an open field. The effects were particularly strong, and dose-dependent, for the ambulatory activity in the open-field arena (forward locomotion) and for rearing activity, whereas the suppression of locomotor activity (i.e. total horizontal activity in the open field) was less conspicuous. The distribution of activity within the open field… 

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