Sedation and weaning from mechanical ventilation: effects of process optimization outside a clinical trial.

@article{Jakob2007SedationAW,
  title={Sedation and weaning from mechanical ventilation: effects of process optimization outside a clinical trial.},
  author={Stephan M. Jakob and Szabina Lubszky and Raymond Friolet and Hans Ulrich Rothen and Anna Kolarova and Jukka Takala},
  journal={Journal of critical care},
  year={2007},
  volume={22 3},
  pages={219-28}
}
PURPOSE We studied the effects of reorganization and changes in the care process, including use of protocols for sedation and weaning from mechanical ventilation, on the use of sedative and analgesic drugs and on length of respiratory support and stay in the intensive care unit (ICU). MATERIALS AND METHODS Three cohorts of 100 mechanically ventilated ICU patients, admitted in 1999 (baseline), 2000 (implementation I, after a change in ICU organization and in diagnostic and therapeutic… CONTINUE READING
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