Sedation after cardiac bypass surgery: comparison of propofol and midazolam in the presence of a computerized closed loop arterial pressure controller.

@article{Chaudhri1992SedationAC,
  title={Sedation after cardiac bypass surgery: comparison of propofol and midazolam in the presence of a computerized closed loop arterial pressure controller.},
  author={S Chaudhri and Gavin N. C. Kenny},
  journal={British journal of anaesthesia},
  year={1992},
  volume={68 1},
  pages={
          98-9
        }
}
Forty patients who had undergone coronary artery graft surgery and who required vasodilator therapy for postoperative hypertension were given infusions of either propofol (2,6,di-isopropylphenol) or midazolam, together with an infusion of morphine for analgesia while ventilation was controlled artificially. Sodium nitroprusside was administered to patients in both groups using a computer-controlled closed loop system. Both agents produced good quality of sedation. Overall times to spontaneous… CONTINUE READING