Secular trends in severe renal failure associated with the use of new antimicrobial agents in critically ill surgical patients

@article{Eichhorn2007SecularTI,
  title={Secular trends in severe renal failure associated with the use of new antimicrobial agents in critically ill surgical patients},
  author={Martin E. Eichhorn and Hilde Wolf and Helmut K{\"u}chenhoff and Mareile Joka and K. -W. Jauch and Wolfgang H. Hartl},
  journal={European Journal of Clinical Microbiology & Infectious Diseases},
  year={2007},
  volume={26},
  pages={395-402}
}
Randomized controlled trials conducted since 2000 have shown that new antibacterial and antifungal agents may reduce the frequency of kidney injury in selected groups of critically ill patients, yet it is unclear whether these benefits translate to the clinical setting. The aim of the present study was to evaluate longitudinally the successive routine implementation of new antimicrobial agents (caspofungin, voriconazole, linezolid) after February 2002 and the association of these agents with… CONTINUE READING