Secrets of success of a human pathogen: molecular evolution of pandemic clones of meticillin-resistant Staphylococcus aureus.

@article{Oliveira2002SecretsOS,
  title={Secrets of success of a human pathogen: molecular evolution of pandemic clones of meticillin-resistant Staphylococcus aureus.},
  author={Duarte Nuno Carvalho Oliveira and Alexander Tomasz and Herminia de Lencastre},
  journal={The Lancet. Infectious diseases},
  year={2002},
  volume={2 3},
  pages={
          180-9
        }
}
The first European isolate of meticillin-resistant Staphylococcus aureus (MRSA) was detected in 1960. Since then MRSA has become a leading cause of nosocomial infections worldwide. Using molecular typing techniques--primarily pulsed-field gel electrophoresis (PFGE)--we identified five major MRSA clones that accounted for almost 70% of the over 3000 MRSA isolates recovered in hospitals mainly in southern and eastern Europe, South America, and the USA. Most of our surveillance studies were done… CONTINUE READING
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