Secretory immunity with special reference to the oral cavity

@inproceedings{Brandtzaeg2013SecretoryIW,
  title={Secretory immunity with special reference to the oral cavity},
  author={P E R Brandtzaeg},
  booktitle={Journal of oral microbiology},
  year={2013}
}
The two principal antibody classes present in saliva are secretory IgA (SIgA) and IgG; the former is produced as dimeric IgA by local plasma cells (PCs) in the stroma of salivary glands and is transported through secretory epithelia by the polymeric Ig receptor (pIgR), also named membrane secretory component (SC). Most IgG in saliva is derived from the blood circulation by passive leakage mainly via gingival crevicular epithelium, although some may be locally produced in the gingiva or salivary… CONTINUE READING
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