Secretory granules are recaptured largely intact after stimulated exocytosis in cultured endocrine cells.

Abstract

Classical cell biology teaches that exocytosis causes the membrane of exocytic vesicles to disperse into the cell surface and that a cell must later retrieve by molecular sorting whatever membrane components it wishes to keep inside. We have tested whether this view applies to secretory granules in intact PC-12 cells. Three granule proteins were labeled… (More)

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@article{Taraska2003SecretoryGA, title={Secretory granules are recaptured largely intact after stimulated exocytosis in cultured endocrine cells.}, author={Justin W Taraska and David Perrais and Mica Ohara-Imaizumi and Shinya Nagamatsu and Wolfhard Almers}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={2003}, volume={100 4}, pages={2070-5} }