Secretory endometrium associated with breakthrough bleeding in estrogen-treated postmenopausal women.

  • Louis Honore
  • Published 1977 in
    European journal of obstetrics, gynecology, and…


Paradoxical secretory changes are described in benign endometria curetted for breakthrough bleeding in postmenopausal women on cyclic low dosage Premarin therapy. This purely histologic study, though favoring progesterone mediation, provides no definitive answer to the problem of pathogenesis. Future correlative morphologic and endocrine investigations are… (More)