Secretory and systemic immunological response in children infected with live attenuated influenza A virus vaccines

@article{Murphy1982SecretoryAS,
  title={Secretory and systemic immunological response in children infected with live attenuated influenza A virus vaccines},
  author={B. Murphy and D. Nelson and P. Wright and E. Tierney and M. Phelan and R. Chanock},
  journal={Infection and Immunity},
  year={1982},
  volume={36},
  pages={1102 - 1108}
}
An enzyme-linked immunosorbent assay was used to measure isotype-specific antibody to purified hemagglutinin (HA) of influenza A virus, using serum and nasal-wash specimens from young children undergoing primary infection with live cold-adapted influenza A/Alaska/77 (H3N2) or A/Hong Kong/77 (H1N1) candidate vaccine virus. The serum antibody response followed the pattern expected for a primary viral infection. Each of 17 vaccinated children had a serum immunoglobulin G (IgG) HA antibody response… Expand
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