Secretory and internalization pathways of mosquito yolk protein precursors

@article{Snigirevskaya1997SecretoryAI,
  title={Secretory and internalization pathways of mosquito yolk protein precursors},
  author={Ekaterina S. Snigirevskaya and Alan R. Hays and Alexander S. Raikhel},
  journal={Cell and Tissue Research},
  year={1997},
  volume={290},
  pages={129-142}
}
The vitellogenic female fat body of the mosquito Aedes aegypti produces three yolk protein precursors that are deposited in the yolk bodies of developing oocytes: vitellogenin, vitellogenic carboxypeptidase (VCP), and 44-kDa protein (44KP). We have used gold immunocytochemistry to investigate the pathways of their secretion in fat body trophocytes and their internalization by oocytes. In fat body trophocytes, all three yolk protein precursors are co-localized in the Golgi complex and secretory… CONTINUE READING

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