Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus

@inproceedings{Zhao2017SecretoryPO,
  title={Secretory Products of the Human GI Tract Microbiome and Their Potential Impact on Alzheimer's Disease (AD): Detection of Lipopolysaccharide (LPS) in AD Hippocampus},
  author={Yuhai Zhao and Vivian R. Jaber and Walter J. Lukiw},
  booktitle={Front. Cell. Infect. Microbiol.},
  year={2017}
}
Although the potential contribution of the human gastrointestinal (GI) tract microbiome to human health, aging, and disease is becoming increasingly acknowledged, the molecular mechanics and signaling pathways of just how this is accomplished is not well-understood. Major bacterial species of the GI tract, such as the abundant Gram-negative bacilli Bacteroides fragilis (B. fragilis) and Escherichia coli (E. coli), secrete a remarkably complex array of pro-inflammatory neurotoxins which, when… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 94 references

The blood-brain barrier in systemic inflammation

Brain, Behavior, and Immunity • 2017
View 4 Excerpts
Highly Influenced

Parkinsonism 5:177

Y. Zhao, V. Jaber, W. J. Lukiw
2016
View 9 Excerpts
Highly Influenced

Alzheimer’s disease and gut microbiota

Science China Life Sciences • 2016
View 4 Excerpts
Highly Influenced

The dynamic blood-brain barrier.

The FEBS journal • 2015
View 5 Excerpts
Highly Influenced

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