Secretory IgA mediates bacterial translocation to dendritic cells in mouse Peyer's patches with restriction to mucosal compartment.

Abstract

In addition to fulfilling its function of immune exclusion at mucosal surfaces, secretory IgA (SIgA) Ab exhibits the striking feature to adhere selectively to M cells in the mouse and human intestinal Peyer's patches (PPs). Subsequent uptake drives the SIgA Ab to dendritic cells (DCs), which become partially activated. Using freshly isolated mouse DCs, we… (More)

Topics

Cite this paper

@article{Kadaoui2007SecretoryIM, title={Secretory IgA mediates bacterial translocation to dendritic cells in mouse Peyer's patches with restriction to mucosal compartment.}, author={Khalil A. Kadaoui and Blaise Corth{\'e}sy}, journal={Journal of immunology}, year={2007}, volume={179 11}, pages={7751-7} }