Secretion of medullipin I by the kidney requires oxygen.

@article{Muirhead1992SecretionOM,
  title={Secretion of medullipin I by the kidney requires oxygen.},
  author={E. Muirhead and B. Brooks and L. W. Byers},
  journal={Journal of hypertension},
  year={1992},
  volume={10 9},
  pages={
          963-7
        }
}
OBJECTIVE To test the hypothesis that the secretion of medullipin I by the kidney involves an oxidative step. DESIGN Medullipin I is secreted by kidney renomedullary interstitial cells and is converted to medullipin II by the liver. Medullipin I can be derived from the kidney in the renal venous effluent by perfusing normal rat kidneys with 95% O2- 5% CO2 at an elevated pressure (180 mmHg). To evaluate whether the secretion of medullipin I involves an oxidative step normal rat kidneys were… Expand