Secretion of interleukin-8 following phagocytosis of Mycobacterium tuberculosis by human monocyte cell lines.

@article{Friedland1992SecretionOI,
  title={Secretion of interleukin-8 following phagocytosis of Mycobacterium tuberculosis by human monocyte cell lines.},
  author={Jon S Friedland and Daniel G Remick and Robin J Shattock and George E. Griffin},
  journal={European journal of immunology},
  year={1992},
  volume={22 6},
  pages={1373-8}
}
Tuberculosis is a major cause of mortality worldwide and incidence is increasing as a result of the AIDS epidemic. Cytokines such as tumor necrosis factor (TNF) are important in the host response to Mycobacterium tuberculosis. TNF is involved in both granuloma formation and has direct anti-mycobacterial activity. This study investigated the secretion of interleukin (IL)-8 following phagocytosis of M. tuberculosis by a human monocytic cell line and by a more phenotypically mature macrophage-like… CONTINUE READING

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