Secretion of cytokines and growth factors into autosomal dominant polycystic kidney disease liver cyst fluid.

@article{Nichols2004SecretionOC,
  title={Secretion of cytokines and growth factors into autosomal dominant polycystic kidney disease liver cyst fluid.},
  author={Matthew T Nichols and Elsa Gidey and Tom Matzakos and Rolf Dahl and Greg Van Stiegmann and Raj Shah and J. J. Grantham and J. Gregory Fitz and R. Brian Doctor},
  journal={Hepatology},
  year={2004},
  volume={40 4},
  pages={836-46}
}
The principal extrarenal manifestation of autosomal dominant polycystic kidney disease (ADPKD) involves formation of liver cysts derived from intrahepatic bile ducts. Autocrine and paracrine factors secreted into the cyst would be positioned to modulate the rate of hepatic cyst growth. The aim of this study was to identify potential growth factors present in human ADPKD liver cyst fluid. Cytokine array and enzyme-linked immunosorbent assay analysis of human ADPKD liver cyst fluid detected… CONTINUE READING