Secretion of an anti-inflammatory, immunomodulatory factor by Schistosomulae of Schistosoma mansoni.

@article{Ramaswamy1995SecretionOA,
  title={Secretion of an anti-inflammatory, immunomodulatory factor by Schistosomulae of Schistosoma mansoni.},
  author={Kalyanasundaram Ramaswamy and Bernard Salafsky and Srilatha Potluri and Yi Xun He and Jing Li and T Tsunefumi Shibuya},
  journal={Journal of inflammation},
  year={1995},
  volume={46 1},
  pages={13-22}
}
Penetration and migration of schistosomulae of Schistosoma mansoni through the skin of mice is associated with reduced inflammatory responses especially after a moderate infection. Previous studies to identify the mechanisms by which schistosomulae of S. mansoni suppress inflammatory responses in human skin showed that the excretory/secretory (ES) products of schistosomulae of s. mansoni contain activities that induce production of the antiinflammatory cytokine IL-1ra from human keratinocytes… CONTINUE READING