Secretion of a platelet-derived growth factor homologue by rat alveolar macrophages exposed to particulates in vitro.

@article{Bauman1990SecretionOA,
  title={Secretion of a platelet-derived growth factor homologue by rat alveolar macrophages exposed to particulates in vitro.},
  author={Mitchel D. Bauman and Anton M Jetten and James C. Bonner and Rakesh K. Kumar and Richard A O Bennett and Arnold R. Brody},
  journal={European journal of cell biology},
  year={1990},
  volume={51 2},
  pages={327-34}
}
Lung macrophages secrete a homologue of platelet-derived growth factor (PDGF) which induces the proliferation of fibroblasts in vitro. In previous studies, we showed that such a PDGF homologue is produced by rat alveolar macrophages and that rat lung fibroblasts have specific receptors for the macrophage-derived PDGF. In this study, we demonstrate the… CONTINUE READING