Secretin induces the apical insertion of aquaporin-1 water channels in rat cholangiocytes.

@article{Marinelli1999SecretinIT,
  title={Secretin induces the apical insertion of aquaporin-1 water channels in rat cholangiocytes.},
  author={R. Marinelli and P. Tietz and L. Pham and L. Rueckert and P. Agre and N. LaRusso},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={1999},
  volume={276 1},
  pages={G280-G286}
}
Aquaporin-1 (AQP1) water channels are present in the apical and basolateral plasma membrane domains of bile duct epithelial cells, or cholangiocytes, and mediate the transport of water in these cells. We previously reported that secretin, a hormone known to stimulate ductal bile secretion, increases cholangiocyte osmotic water permeability and stimulates the redistribution of AQP1 from an intracellular vesicular pool to the cholangiocyte plasma membrane. Nevertheless, the target plasma membrane… Expand
The Role of Aquaporin Water Channels in Fluid Secretion by the Exocrine Pancreas
Unimpaired osmotic water permeability and fluid secretion in bile duct epithelia of AQP1 null mice.
Differential regulation of vacuolar H+-ATPase and Na+/H+ exchanger 3 in rat cholangiocytes after bile duct ligation
Expression and immunolocalization of aquaporin water channels in rat exocrine pancreas.
Aquaporin 2 is a vasopressin-independent, constitutive apical membrane protein in rat vas deferens.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 42 REFERENCES
Secretin Promotes Osmotic Water Transport in Rat Cholangiocytes by Increasing Aquaporin-1 Water Channels in Plasma Membrane
Cholangiocytes express the aquaporin CHIP and transport water via a channel-mediated mechanism.
  • S. Roberts, M. Yano, +4 authors N. LaRusso
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1994
Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane.
Solute and water transport pathways in cholangiocytes.
Distribution of the aquaporin CHIP in secretory and resorptive epithelia and capillary endothelia.
Vasopressin increases AQP-CD water channel in apical membrane of collecting duct cells in Brattleboro rats.
Rat Hepatocytes Transport Water Mainly via a Non-channel-mediated Pathway (*)
...
1
2
3
4
5
...