Secretin Stimulates Cyclic AMP Formation in the Rat Brain

@article{Fremeau1986SecretinSC,
  title={Secretin Stimulates Cyclic AMP Formation in the Rat Brain},
  author={R. Fremeau and L. Korman and T. Moody},
  journal={Journal of Neurochemistry},
  year={1986},
  volume={46}
}
The effects of secretin on cyclic AMP levels in the rat brain were determined. Incubation of rat brain frontal cortex slices with secretin or the structurally related peptides peptide histidine leucine (PHI) or vasoactive intestinal polypeptide (VIP) in the presence of 10 mM theophylline resulted in a dose‐dependent increase in the cyclic AMP levels. The half‐maximal increase in cyclic AMP occurred using a 1 μM dose of secretin or a 2 μM dose of PHI or VIP. Preincubation of slices with secretin… Expand
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Effects of secretin on extracellular GABA and other amino acid concentrations in the rat hippocampus.
Effects of secretin on extracellular amino acid concentrations in rat hippocampus
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