Secreted autotransporter toxin (Sat) triggers autophagy in epithelial cells that relies on cell detachment.

Abstract

The secreted autotransporter toxin, Sat, which belongs to the subfamily of serine protease autotransporters of Enterobacteriaceae, acts as a virulence factor in extraintestinal and intestinal pathogenic strains of Escherichia coli. We observed that HeLa cells exposed to the cell-free culture supernatant of recombinant strain AAEC185p(Sat-IH11128) producing… (More)
DOI: 10.1111/j.1462-5822.2011.01595.x

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