Secreted Frizzled Related Protein 3 in Chronic Heart Failure: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)

@inproceedings{Askevold2015SecretedFR,
  title={Secreted Frizzled Related Protein 3 in Chronic Heart Failure: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)},
  author={Erik Tandberg Askevold and Lars Gullestad and St{\aa}le Haugset Nymo and John Kjekshus Kjekshus and Arne Yndestad and Roberto C. Latini and John G. F. Cleland and John J V McMurray and P{\aa}l Aukrust and Thor Ueland and Philippe Rouet},
  booktitle={PloS one},
  year={2015}
}
BACKGROUND We have previously demonstrated an association between increased sFRP3 expression and adverse outcome in a population of HF irrespective of cause and left ventricular ejection fraction. In this study we evaluated the prognostic value of sFRP3 in older patients with chronic systolic HF of ischemic origin. METHODS We evaluated sFRP3, by tertiles, as a risk factor for the primary endpoint (cardiovascular [CV] mortality, nonfatal myocardial infarction, nonfatal stroke), all-cause… CONTINUE READING

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