Secretagogues cause a preferential discharge of large size granules in rat pancreas.

@article{Beaudoin1984SecretagoguesCA,
  title={Secretagogues cause a preferential discharge of large size granules in rat pancreas.},
  author={Adrien R. Beaudoin and Gilles Grondin and Martin Filion and Andr{\'e} Lord},
  journal={Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire},
  year={1984},
  volume={62 12},
  pages={1288-92}
}
We have compared the diameters of zymogen granules in the exocrine pancreas of fasted or stimulated rats. The average granule diameter was 0.73 microns +/- 0.18 SD (sample size, 1460) in fasted animals and significantly reduced to 0.68 microns +/- 0.17 SD (sample size, 860) after 120 min and two intraperitoneal injections of urecholine. Reduction of granule size was attributable to the preferential discharge of large size granules. The range between first and third quartiles of the distribution… CONTINUE READING