Secretagogue-induced translocation of CRHSP-28 within an early apical endosomal compartment in acinar cells.

Abstract

Ca(2+)-regulated heat-stable protein (CRHSP-28) is a member of the TPD52 protein family that has been shown to regulate Ca(2+)-dependent secretory activity in pancreatic acinar cells. Immunofluorescence microscopy of isolated lobules demonstrated that CRHSP-28 is localized to a supranuclear apical compartment in acini and accumulates immediately below the… (More)

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