Secretagogue and second messenger-activated Cl− permeabilities in isolated pancreatic zymogen granules

@article{Fuller1989SecretagogueAS,
  title={Secretagogue and second messenger-activated Cl− permeabilities in isolated pancreatic zymogen granules},
  author={Catherine M. Fuller and Hanns H. Deetjen and Albrecht Piiper and Irene Schulz},
  journal={Pfl{\"u}gers Archiv},
  year={1989},
  volume={415},
  pages={29-36}
}
Previous studies of enzyme secretion from isolated pancreatic acinar cells and of isolated zymogen granules (ZG) have reported that both a Cl− and a K+ permeability are present on the ZG membrane. It has been suggested that ion influx via these permeability pathways, followed by water movement is required for granular swelling which appears to be intimately… CONTINUE READING