Secoverine hydrochloride is a muscarinic antagonist in human isolated gastrointestinal muscle and myometrium

@article{Sanger1981SecoverineHI,
  title={Secoverine hydrochloride is a muscarinic antagonist in human isolated gastrointestinal muscle and myometrium},
  author={G. Sanger and A. Bennett},
  journal={Journal of Pharmacy and Pharmacology},
  year={1981},
  volume={33}
}
Secoverine is a new antimuscarinic agent thought to be selective for smooth muscle. We have found it to be a potent anticholinergic antagonist of acetylcholine in strips of human gastrointestinal and uterine muscle. The pA2 values in gut longitudinal and circular muscle and myometrium were 9·1, 9·3 and 8·6 respectively. 
10 Citations
Muscarinic receptor differentiation.

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