Secondary structure of nrDNA Internal Transcribed Spacers as a useful tool to align highly divergent species in phylogenetic studies

@inproceedings{Giudicelli2017SecondarySO,
  title={Secondary structure of nrDNA Internal Transcribed Spacers as a useful tool to align highly divergent species in phylogenetic studies},
  author={Giovanna C{\^a}mara Giudicelli and Geraldo M{\"a}der and Gustavo Adolfo Silva-Arias and Priscilla Mena Zamberlan and Sandro L Bonatto and Loreta B Freitas},
  booktitle={Genetics and molecular biology},
  year={2017}
}
Recently, it has been suggested that internal transcribed spacer (ITS) sequences are under selective constraints to preserve their secondary structure. Here, we investigate the patterns of the ITS nucleotide and secondary structure conservation across the Passiflora L. genus to evaluate the potential use of secondary structure data as a helpful tool for the alignment in taxonomically complex genera. Considering the frequent use of ITS, this study also presents a perspective on future analyses… CONTINUE READING

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