Secondary structure, 1H, 13C and 15N resonance assignments and molecular interactions of the dishevelled DIX domain.

Abstract

Dishevelled (Dvl) is a positive regulator of the canonical Wnt signaling pathway, which regulates the levels of beta-catenin. The beta-catenin oncoprotein depends upon the association of Dvl and Axin proteins through their DIX domains, and its accumulation directs the expression of specific developmental-related genes at the nucleus. Here, the (1)H, (13)C… (More)

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.