Secondary pulmonary alveolar proteinosis complicating myelodysplastic syndrome results in worsening of prognosis: a retrospective cohort study in Japan

@inproceedings{Ishii2014SecondaryPA,
  title={Secondary pulmonary alveolar proteinosis complicating myelodysplastic syndrome results in worsening of prognosis: a retrospective cohort study in Japan},
  author={Haruyuki Ishii and John F Seymour and Ryushi Tazawa and Yoshikazu Inoue and Naoyuki Uchida and Aya Nishida and Yoshihito Kogure and Takeshi Saraya and Keisuke Tomii and Toshinori Takada and Yuko Itoh and Masayuki Hojo and Toshio Ichiwata and Hajime Goto and Koh Nakata},
  booktitle={BMC pulmonary medicine},
  year={2014}
}
BACKGROUND Secondary pulmonary alveolar proteinosis (sPAP) is a very rare lung disorder comprising approximately 10% of cases of acquired PAP. Hematological disorders are the most common underlying conditions of sPAP, of which 74% of cases demonstrate myelodysplastic syndrome (MDS). However, the impact of sPAP on the prognosis of underlying MDS remains unknown. The purpose of this study was to evaluate whether development of sPAP worsens the prognosis of MDS. METHODS Thirty-one cases of sPAP… CONTINUE READING
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