Secondary pulmonary alveolar proteinosis in hematologic malignancies.


Pulmonary alveolar proteinosis (PAP), characterized by deposition of intra-alveolar PAS positive protein and lipid rich material, is a rare cause of progressive respiratory failure first described by Rosen et al. in 1958. The intra-alveolar lipoproteinaceous material was subsequently proven to have been derived from pulmonary surfactant in 1980 by Singh et… (More)
DOI: 10.1016/j.hemonc.2014.09.003


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