Secondary pathology following contusion, dislocation, and distraction spinal cord injuries

@article{Choo2008SecondaryPF,
  title={Secondary pathology following contusion, dislocation, and distraction spinal cord injuries},
  author={Anthony Min-Te Choo and Jie Liu and Marcel F. Dvorak and Wolfram Tetzlaff and T R A - Bagby Fdn Oxland},
  journal={Experimental Neurology},
  year={2008},
  volume={212},
  pages={490-506}
}
Preclinical studies for spinal cord injury (SCI) have utilized transection and contusion injury paradigms even though human SCIs occur by a spectrum of primary injury mechanisms such as spinal cord contusion from vertebral burst fracture, shearing from fracture-dislocation, and stretching from distraction injuries. We contrasted the neuropathology in animal models mimicking these clinically relevant injuries at an early 3-hour time-point in order to relate patterns of secondary pathology to the… CONTINUE READING

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