Secondary metabolites with nematicidal and antimicrobial activity from nematophagous fungi and Ascomycetes

@article{Anke1995SecondaryMW,
  title={Secondary metabolites with nematicidal and antimicrobial activity from nematophagous fungi and Ascomycetes},
  author={H. Anke and M. Stadler and A. Mayer and O. Sterner},
  journal={Botany},
  year={1995},
  volume={73},
  pages={932-939}
}
Screening of nematode-trapping fungi for antimicrobial and nematicidal activities gave three new antimicrobial metabolites from cultures of five Arthrobotrys strains. The compounds exhibited no nematicidal activities towards Caenorhabditis elegans and Meloidogyne incognita. From trap-forming submerged cultures of Arthrobotrys conoides, linoleic acid was isolated as a nematicidal principle. Its production increased with the number of traps formed in both Arthrobotrys oligospora and Arthrobotrys… Expand
Metabolites from nematophagous fungi and nematicidal natural products from fungi as alternatives for biological control. Part II: metabolites from nematophagous basidiomycetes and non-nematophagous fungi
In this second section of a two-part mini-review article, we introduce 101 further nematicidal and non-nematicidal secondary metabolites biosynthesized by nematophagous basidiomycetes orExpand
New nematicidal and antimicrobial secondary metabolites from a new species in the new genus, Pseudobambusicola thailandica
TLDR
A fungal strain isolated from a plant sample was shown to represent an undescribed species, as inferred from a combination of morphological and molecular phylogenetic methods, and a phylogenetic tree with the newly generated sequences clustering in a separate branch was revealed. Expand
Nematode-Toxic Fungi and their Nematicidal Metabolites
This chapter summarizes more than 200 compounds from fungi that have been shown to possess nematicidal activities. These compounds belong to diverse chemical groups including alkaloid, quinone,Expand
Metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst. V. Production, isolation and biological activities of bromine-containing mycorrhizin and lachnumon derivatives and four additional new bioactive metabolites.
TLDR
Eight novel bioactive metabolites were isolated from submerged cultures of the ascomycete Lachnum papyraceum (Karst.) Karst, when CaBr2 was added to the cultures after the onset of secondary metabolism, suggesting DNA-alkylating properties. Expand
Screening and Isolation of Anti-Nematodal Metabolites Against Bursaphelenchus xylophilus Produced by Fungi and Plant
Several plants and fungi were tested in random screening of anti-nemato-dal metabolites against Bursaphelenchus xylophilus using an immersion test. Among 30 species of the terrestrial plants tested,Expand
NEMATICIDAL POTENTIAL OF CULTURE FILTRATES OF SOIL FUNGI ASSOCIATED WITH RHIZOSPHERE AND RHIZOPLANE OF CULTIVATED AND WILD PLANTS
TLDR
Culture filtrates of several isolates of fungi, isolated from rhizosphere and rhizoplane of cultivated and wild plants exhibited significant nematicidal activity on Meloidogyne javanica, by killing 2 nd stage juveniles at varying degrees. Expand
Influence of bioactive metabolites extracted from three species of nematode-trapping fungi on the growth of Escherichia coli and Staphylococcus aureus
The effect of different concentrations of cultures filtrate, crude filtrate extracts and fungal mycelia crude extracted from three species of nematode-trapping fungi (Arthrobotrys dactyloides,Expand
New metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst. VIII. Isolation, structure determination and biological activities of minor metabolites structurally related to mycorrhizin A.
TLDR
Five new minor metabolites have been isolated from extracts of the culture fluids of the ascomycete Lachnum papyraceum and are structurally related to the nematicidal and antibiotic mycorrhizin A, which also is produced by the fungus. Expand
Nematicidal Effect of Root-knot Nematode (Meloidogyne incognita) by Biological Nematicide
TLDR
The results suggested that the mixture of microorganisms and plant extract were more effective biological nematicide than the case of only microorganism or plant extract for nematode control. Expand
Orbiliaceous nematode-trapping fungi and related species in Western Australia and their biological activities
Twenty-nine isolates of orbiliaceous nematode-trapping fungi including 19 species of the genera Arthrobotrys, Dactylellina, and Gamsylella were obtained from various substrata ranging from woodExpand
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Metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst. V. Production, isolation and biological activities of bromine-containing mycorrhizin and lachnumon derivatives and four additional new bioactive metabolites.
TLDR
Eight novel bioactive metabolites were isolated from submerged cultures of the ascomycete Lachnum papyraceum (Karst.) Karst, when CaBr2 was added to the cultures after the onset of secondary metabolism, suggesting DNA-alkylating properties. Expand
Fatty acids and other compounds with nematicidal activity from cultures of Basidiomycetes.
TLDR
In a screening for nematicidal activities in cultures of Basidiomycetes, cultures of Pleurotus pulmonarius and Hericium coralloides exhibited toxic effects towards the saprophytic nematode Caenorhabditis elegans, with the most active compounds being 1 and 2 with LD50 values between 5 and 10 ppm. Expand
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TLDR
The production of these compounds by Nematoctonus, a known anamorph of Hohenbuehelia reveals also a close chemotaxonomic relationship between the sexual and imperfect stage of these basidiomycetes. Expand
New metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst. VI. Structure determination of non-halogenated metabolites structurally related to mycorrhizin A.
TLDR
Four new biologically active non-halogenated metabolites isolated from submerged cultures of the ascomycete Lachnum papyraceum are described, structurally related to the antibiotic mycorrhizin A. Expand
Lachnumon and lachnumol a, new metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst. I. Producing organism, fermentation, isolation and biological activities.
Several chlorinated metabolites with nematicidal, antimicrobial, and cytotoxic activities were isolated from submerged cultures of the ascomycete Lachnum papyraceum. Three compounds were identifiedExpand
Metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst. III. Production of novel isocoumarin derivatives, isolation, and biological activities.
TLDR
During investigations on the influence of CaBr2 on the secondary metabolism of Lachnum papyraceum, the production of mycorrhizins and lachnumon type antibiotics was strongly inhibited in bromide-containing culture media, and six isocoumarin derivatives exhibited only weak antimicrobial, cytotoxic, phytotoxic and nematicidal activities. Expand
A Nematotoxin produced by the Nematophagous Fungus Arthrobotrys oligospora Fresenius
TLDR
It is suggested that a toxin, capable of paralysing or killing, may be secreted by the adhesive trapping organs and act externally, or that such a substance may be transported internally by way of the fine penetration peg through the nematode cuticle. Expand
Proteases and Their Involvement in the Infection and Immobilization of Nematodes by the Nematophagous Fungus Arthrobotrys oligospora
TLDR
The effects of PMSF on the immobilization of nematodes were probably due to serine proteases produced by the fungus, since the effects were observed when unbound inhibitor was washed away from the fungus before the nematode was added to the system. Expand
Occurrence and metabolic significance of microbodies in trophic hyphae of the nematophagous fungus Arthrobotrys oligospora
TLDR
The results suggest that part of the nutrients released from the nematode are first converted into lipids by the fungus which in turn are degraded via the β-oxidation pathway and further metabolized to support growth of new vegetative hyphae. Expand
New metabolites with nematicidal and antimicrobial activities from the ascomycete Lachnum papyraceum (Karst.) Karst. VII. Structure determination of brominated lachnumon and mycorrhizin A derivatives.
TLDR
The structure determination of lach numon B1 and lachnumon B2 and mycorrhizin B2, brominated derivatives of Lachnum papyraceum, are described, which exhibit similar antimicrobial and nematicidal activity as their chlorinated analogues. Expand
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