Secondary metabolites from three Florida sponges with antidepressant activity.

  title={Secondary metabolites from three Florida sponges with antidepressant activity.},
  author={Anna Kochanowska and Karumanchi V. Rao and Suzanne Childress and Abir T. El-Alfy and Rae R. Matsumoto and Michelle Kelly and Gina S Stewart and Kenneth J. Sufka and Mark T. Hamann},
  journal={Journal of natural products},
  volume={71 2},
Brominated indole alkaloids are a common class of metabolites reported from sponges of the order Verongida. Herein we report the isolation, structure determination, and activity of metabolites from three Florida sponges, namely, Verongula rigida (order Verongida, family Aplysinidae), Smenospongia aurea, and S. cerebriformis (order Dictyoceratida, family Thorectidae). All three species were investigated chemically, revealing similarities in secondary metabolites. Brominated compounds, as well as… CONTINUE READING
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