Secondary effects of catalytic diesel particulate filters: reduced aryl hydrocarbon receptor-mediated activity of the exhaust.

@article{Wenger2008SecondaryEO,
  title={Secondary effects of catalytic diesel particulate filters: reduced aryl hydrocarbon receptor-mediated activity of the exhaust.},
  author={Daniela Wenger and Andreas C Gerecke and Norbert Victor Heeb and Markus Zennegg and Martin Kohler and Hanspeter Naegeli and Renato Zenobi},
  journal={Environmental science & technology},
  year={2008},
  volume={42 8},
  pages={2992-8}
}
Diesel exhaust contains numerous toxic substances that show different modes of action such as triggering aryl hydrocarbon receptor (AhR)-mediated pathways. We investigated AhR-mediated activity of exhaust generated by a heavy-duty diesel engine operated with or without iron- or copper/iron-catalyzed diesel particulate filters (DPFs). AhR agonists were quantified using the DR-CALUX reporter gene assay (exposure of cells for 24 h). We found 54-60 ng 2,3,7,8-tetrachlorodibenzo-p-dioxin CALUX… CONTINUE READING