Secondary Structure Preferences of the Anthrax Toxin Protective Antigen Translocase.

Abstract

In order for many proteins to move across hydrophobic membrane bilayers, they must be unfolded and translocated by a membrane-embedded channel. These translocase channels interact with the substrate proteins they translocate via hydrophobic pore loops and cleft structures called clamps. The molecular basis for how clamps facilitate unfolding and… (More)
DOI: 10.1016/j.jmb.2017.01.015

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