Secondary Progressive Multiple Sclerosis: Definition and Measurement.

  title={Secondary Progressive Multiple Sclerosis: Definition and Measurement.},
  author={Domenico Plantone and Floriana De Angelis and Anisha Doshi and Jeremy Chataway},
  journal={CNS drugs},
  volume={30 6},
Secondary progressive multiple sclerosis (SPMS) is diagnosed retrospectively and involves a clinical course characterized by a progressive accumulation of neurological disability, independent of relapses, following an initial relapsing-remitting (RR) phase. Our incomplete understanding of the pathological mechanisms underlying neurodegeneration in multiple… CONTINUE READING